Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]- Chemical Properties

Boiling point:

1466.3±65.0 °C(Predicted)

Density 

1.38±0.1 g/cm3(Predicted)

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

pka

9.86±0.26(Predicted)

color 

Off-White to Pale Yellow

Stability:

Hygroscopic

Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]- Usage And Synthesis

Uses

Des-(5-(threo-3-hydroxy-L-ornithine)) Caspofungin Acetate is an intermediate in the preparation of Caspofungin. It is the impurity of Caspofungin Acetate (C184900), an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections.