2-Cyano-4-fluoropyridine Chemical Properties

Melting point:

72-74℃

Boiling point:

221℃

Density 

1.24

Flash point:

88℃

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

form 

powder

pka

-1.44±0.10(Predicted)

color 

Yellow

Safety Information

RIDADR 

UN3439

HS Code 

2933399990

2-Cyano-4-fluoropyridine Usage And Synthesis

Application

The 2-cyano-4-fluoropyridine is a novel fluorine-containing medical intermediate and has wide application in the field of medicine. 

Preparation

(1)4-chloropyridine-2-formamide is prepared by taking 4-chloropyridine-2-methyl formate and ammonia water as raw materials through an ammonolysis reaction; (2) dehydrating 4-chloropyridine-2-formamide under the action of a dehydrating agent to obtain 2-cyano-4-chloropyridine; (3) 2-cyano-4-chloropyridine is subjected to halogen exchange reaction to obtain 2-cyano-4-fluoropyridine.

2-Cyano-4-fluoropyridine(847225-56-3)Related Product Information

• 5-Chloro-2-cyanopyridine
• 2-Cyano-5-nitropyridine
• (5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-ACETONITRILE
• 6-Methylpyridine-2-carbonitrile
• 3-Bromo-2-cyanopyridine
• 2-Cyano-5-fluoropyridine
• 4-CHLORO-PYRIDINE-2-CARBONITRILE
• 5-Bromo-6-methyl-2-pyridinecarbonitrile
• 2-Cyano-5-methylpyridine
• 4-Bromomethyl-2-cyanobiphenyl
• 5-Bromo-2-pyridinecarbonitrile
• 2-CYANO-4-METHYLPYRIDINE
• 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE
• 2,6-DICHLORO-3-CYANO-5-FLUOROPYRIDINE
• 4-CYANO-2-FLUOROPYRIDINE
• 3-CYANO-2-FLUOROPYRIDINE
• 2-CYANO-3-FLUOROPYRIDINE
• 3-CYANO-5-FLUOROPYRIDINE