Basic information Safety Supplier Related

1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE

Basic information Safety Supplier Related

1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Basic information

Product Name:
1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE
Synonyms:
  • 1,2,3,4-Tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
  • 1-Tosyl-2,3,4,5-tetrahydro-1H-1-benzazepine-5-one
  • 1-Tosyl-2,3-dihydro-1H-1-benzazepine-5(4H)-one
  • 1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE
  • 1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • 1-[(4-Methylbenzene)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one
  • 1,2,3,4-tetrahydro-1-tosylbenzo[b]azepin-5-one
  • 1,2,3,4-tetrahydro-1-(4-Methylbenzenesulfonyl)-1-benzazepin-5-one
CAS:
24310-36-9
MF:
C17H17NO3S
MW:
315.39
EINECS:
1312995-182-4
Product Categories:
  • pharmacetical
Mol File:
24310-36-9.mol
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1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Chemical Properties

Melting point:
126 °C(Solv: methanol (67-56-1))
Boiling point:
489.7±48.0 °C(Predicted)
Density 
1.286±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-3?+-.0.20(Predicted)
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Safety Information

HazardClass 
IRRITANT
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1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Usage And Synthesis

Uses

1,2,3,4-Tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one is an intermediate used to prepare nonpeptide vasopressin V2 receptor antagonist tetrahydro-1H-benzazepines. It is also used to synthesize 4''-[(4,4-difluoro-5-methylidene-2,3,4,5-tetrahydro-1H-1-benzoazepin-1-yl)carbonyl]-2-phenylbenzanilide derivatives as non-peptide arginine vasopressin antagonists for both V1A and V2 receptors.

1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONESupplier

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