Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride Chemical Properties

Melting point:

141-142° (Lumma); mp 137° and mp 142° (Argentieri)

storage temp. 

2-8°C

solubility 

H2O: ≥16mg/mL

pka

pKa1 7.60; pKa2 9.51(at 25℃)

form 

powder

color 

white to beige

Safety Information

WGK Germany 

3

Toxicity

LD50 i.p. in mice: 250-300 mg/kg (Lumma); LD50 in mice, rats, dogs (mg/kg): 96, 92, 143-175 i.v.; 1,800, 3,200, 500-1,000 orally (Argentieri)

Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride Usage And Synthesis

Uses

Cardiac depressant (anti-arrhythmic).

Uses

Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness.

Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride(101526-62-9)Related Product Information

• Semaglutide
• N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE
• Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride
• 4-(Methylsulfonylamino)benzylamine
• 4-(METHYLSULFONYLAMINO)BENZYLAMINEHYDROCHLORIDE