NC 190
NC 190 Basic information
- Product Name:
- NC 190
- Synonyms:
-
- NC 190
- NC190 sodium
- NC190 sodium,NC-190 sodium
- CAS:
- 120602-99-5
- MF:
- C23H21N4O5.Na
- MW:
- 456.432
- Mol File:
- 120602-99-5.mol
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NC 190 Usage And Synthesis
Description
NC190 is a topoisomerase II-inhibitor that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells with an IC50 of 0.019 microg/ml (0.042 microM) when cultured with NC-190 for 48 h. NC-190 potently suppressed DNA synthesis, with 90% inhibition observed at 0.1 microg/ml of NC-190.