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ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Phosphine ligand >  (4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE

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(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE Basic information

Product Name:
(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE
Synonyms:
  • (S)-(-)-2-[(DIPHENYLPHOSPHINO)PHENYL]-4-(1-METHYLETHYL)-4,5-DIHYDROOXAZOLE
  • (S)-(-)-2-[2-(DIPHENYLPHOSPHINO)PHENYL]-4-(1-ISOPROPYL)-4,5-DIHYDROOXAZOLE
  • (S)-(-)-2-[2-(DIPHENYLPHOSPHINO)PHENYL]-4-(1-METHYLETHYL)-4,5-DIHYDROOXAZOLE
  • (S)-(-)-2-[2-(DIPHENYLPHOSPHINO)PHENYL]-4,5-DIHYDRO-4-ISOPROPYLOXAZOLE
  • (S)-(-)-2-[2-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYL-2-OXAZOLINE
  • (-)(4S)-2-[2-(DIPHENYLPHOSPHINO)PHENYL]-4-(2-PROPYL)OXAZOLINE
  • (4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE
  • (S)-(-)-2-[2-(Diphenylphosphino)phenyl]-4-isopropyl-2-
CAS:
148461-14-7
MF:
C24H24NOP
MW:
373.43
Product Categories:
  • Chiral Phosphine
  • PHOX Series
  • organophosphine ligand
Mol File:
148461-14-7.mol
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(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE Chemical Properties

Melting point:
85-90 °C
alpha 
-44° (c 1.4, CHCl3)
Boiling point:
492.7±28.0 °C(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
4.31±0.70(Predicted)
form 
Powder
color 
white
optical activity
[α]20/D 48±3°, c = 1% in chloroform
Sensitive 
air sensitive
BRN 
5879302
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-24/25
WGK Germany 
3
10-23
Hazard Note 
Irritant
HS Code 
29349990

MSDS

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(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLE Usage And Synthesis

Chemical Properties

White crystalline powder

Reactions

  1. Chiral ligand used in the asymmetric reduction of highly substituted olefins.
  2. Chiral ligand used in the enantioselective Heck reaction. The success of the reaction is due to the fact that the catalytic system does not promote double bond isomerization.
  3. Chiral ligand used in the entantioselective palladium-catalyzed allylic substitution of sodium benzotriazole.
  4. Decarboxylative allylic alkylation.

(4S)-(-)-4,5-DIHYDRO-2-[2'-(DIPHENYLPHOSPHINO)PHENYL]-4-ISOPROPYLOXAZOLESupplier

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