Ethyl picolinate Chemical Properties

Melting point:

2 °C (lit.)

Boiling point:

240-241 °C (lit.)

Density 

1.119 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.511(lit.)

Flash point:

225 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Liquid

pka

1.83±0.10(Predicted)

color 

Clear yellow or pink

Water Solubility 

miscible

BRN 

122485

InChIKey

FQYYIPZPELSLDK-UHFFFAOYSA-N

LogP

0.870

CAS DataBase Reference

2524-52-9(CAS DataBase Reference)

NIST Chemistry Reference

2-Pyridinecarboxylic acid, ethyl ester(2524-52-9)

EPA Substance Registry System

Ethyl picolinate (2524-52-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HS Code 

29333999

MSDS

• Language:English Provider:Ethyl pyridine-2-carboxylate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Ethyl picolinate Usage And Synthesis

Chemical Properties

clear yellowish or pink liquid

Uses

Ethyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate.

Uses

Ethyl picolinate can be used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 43, p. 1028, 1995 DOI: 10.1248/cpb.43.1028

Ethyl picolinate (2524-52-9)Related Product Information

• Urethane
• DL-α-Tocopherol
• RESMETHRIN
• Ethyl acrylate
• Diphenolic acid
• 4-(Diethylamino)salicylaldehyde
• Ethyl acetate
• Ethyl cellulose
• Ethyl cyanoformate
• Pyridine
• CHLOROETHANE
• 5-Chlorovaleric acid
• Ethylbenzene
• Ethylparaben
• Ethanol
• Ethyl formate
• Pralmorelin
• Benzocaine