N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(DIBUTYLAMINO)STYRYL)PYRIDINIUM DIBROMIDE Chemical Properties

storage temp. 

−20°C

solubility 

DMSO: soluble

form 

solid

color 

dark red

Appearance

light red solid

Safety Information

Safety Statements 

24/25-22

WGK Germany 

3

HS Code 

32041900

MSDS

• Language:English Provider:ACROS

N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(DIBUTYLAMINO)STYRYL)PYRIDINIUM DIBROMIDE Usage And Synthesis

Description

SynaptoProbe® Green is an analog of FM^®1-43, a widely used green fluorescent dye for studying synaptic activity in the synapses or neuromuscular junctions by staining synaptic vesicles.

This water-soluble and non-toxic to cells dye is nonfluorescent in an aqueous medium but becomes highly fluorescent after embedding into the outer leaflet of the cell membrane. When a neuron actively releases neurotransmitters, the dye becomes internalized within the recycled synaptic vesicles and stains the nerve terminals.

SynaptoProbe® Green can be used to visualize synaptic vesicles and their exocytosis and endocytosis in living neurons, identify actively firing neurons, and investigate the mechanisms of activity-dependent vesicle cycling. It is also helpful for the visualization of shear stress-induced plasma membrane damage in fibroblasts.

Uses

Water Soluble fluorescent RH probe

Uses

Biological probe for membrane dynamics.

Definition

ChEBI: FM 1-43 dye is an organic bromide salt, a quaternary ammonium salt, a tertiary amine and a pyridinium salt. It has a role as a fluorochrome. It contains a FM 1-43(2+).

Biological Activity

A fluorescent nerve terminal dye suitable for monitoring synaptic activity at synapses and at neuromuscular junctions.

Abs/Em Maxima

492/594 nm

Excitation / Emission Maximum

541 nm/567 nm

Extinction Coefficient

55800

N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(DIBUTYLAMINO)STYRYL)PYRIDINIUM DIBROMIDE(149838-22-2)Related Product Information

• FM479
• FM-381
• N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(DIBUTYLAMINO)STYRYL)PYRIDINIUM DIBROMIDE
• 4-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95
• 4-((E)-2-[4-(DIETHYLAMINO)PHENYL]ETHENYL)-1-[3-(TRIETHYLAMMONIO)PROPYL]PYRIDINIUM DIBROMIDE
• FM(TM) 1-84