BIOCYTIN HYDROCHLORIDE Chemical Properties

storage temp. 

−20°C

solubility 

good in water, DMSO

form 

powder

color 

white to off-white

Appearance

white powder

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

BIOCYTIN HYDROCHLORIDE Usage And Synthesis

Description

Biocytin (ε-biotinoyl-L-lysine) is a derivative of D-biotin and L-lysine. The compound has both a carboxyl group and an amino group, due to which it is widely used as a spacer and a component of trifunctional crosslinkers in the modification of proteins.

Biocytin, as a biotinidase cofactor, can be used to determine the specificity of biotinidases and to study the kinetics and mechanisms of cellular delivery.

Biocytin is also used as an anterograde neurotracer.

Biocytin hydrochloride has a high solubility in aqueous solutions; it can be used to biotinylate proteins under slightly acidic conditions (pH 4-6) using EDAC, which distinguishes it from N-hydroxysuccinimide (NHS) esters of biotin.

Biological Activity

Biocytin is used as a substrate to study the specificity and kinetics of biotinidase(s), to measure biotinidase deficiency and as a model compound to study various uptake mechanisms of cells and tissues.

BIOCYTIN HYDROCHLORIDE(98930-70-2)Related Product Information

• H-LYS(ME)-OH HCL
• BIOCYTIN HYDROCHLORIDE
• (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID
• Biocytin
• 1-Amino-2-propanethiol hydrochloride
• 6-Acetamidohexanoic acid
• N-EPSILON-ACETYL-L-LYSINE
• 5-(Biotinamido)pentylamine