ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > (S)-1-Amino-2-hydroxymethylindoline
(S)-1-Amino-2-hydroxymethylindoline
(S)-1-Amino-2-hydroxymethylindoline Basic information
- Product Name:
- (S)-1-Amino-2-hydroxymethylindoline
- Synonyms:
-
- (2S)-1-aMino-2,3-dihydro-1H-Indole-2-Methanol
- (S)-1-Amino-2-hydroxymethylindoline
- 1H-Indole-2-methanol, 1-amino-2,3-dihydro-, (2S)-
- CAS:
- 27719-98-8
- MF:
- C9H12N2O
- MW:
- 164.2
- Mol File:
- 27719-98-8.mol
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(S)-1-Amino-2-hydroxymethylindoline Chemical Properties
- Melting point:
- 81.5-82.7 °C (racemate)
- solubility
- readily sol methanol, ethanol; insol hexane, ether.
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(S)-1-Amino-2-hydroxymethylindoline Usage And Synthesis
Preparation
2-hydroxymethylindoline is resolved with (S)-(+)-Mandelic Acid to give (S)-(+)-2-
hydroxymethylindoline, which is then nitrosated and reduced to produce (S)-1-Amino-2-hydroxymethylindoline (eq 1). (R)-1-Amino-2-hydroxymethylindoline is also available
by a similar procedure.
storage
(S)-1-Amino-2-hydroxymethylindoline is very air sensitive. Store under nitrogen or argon at -20 °C. Use in a fume hood.