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7'-OH-N-trityl Morpholino thyMine

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7'-OH-N-trityl Morpholino thyMine Basic information

Product Name:
7'-OH-N-trityl Morpholino thyMine
Synonyms:
  • 7'-OH-N-trityl Morpholino thyMine
  • 1-((2R,6S)-6-(hydroxyMethyl)-4-tritylMorpholin- 2-yl)-5-MethylpyriMidine-2,4-(1H,3H)-dione
  • 1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
  • 7'-Hydroxy-N-tritylmorpholino thymine monomer
  • 1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2, 4(1H, 3H)-dione
  • PMO Thymidine Precusor
  • PMO-T Precusor
  • Morpholino-5-Me-U
CAS:
914361-76-5
MF:
C29H29N3O4
MW:
483.56
Mol File:
914361-76-5.mol
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7'-OH-N-trityl Morpholino thyMine Chemical Properties

Density 
1.259±0.06 g/cm3(Predicted)
pka
9.51±0.10(Predicted)
InChIKey
SINOYLIIFJJPCM-IZZNHLLZSA-N
SMILES
C1(=O)N([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C=C(C)C(=O)N1
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7'-OH-N-trityl Morpholino thyMine Usage And Synthesis

Description

7'-OH-N-trityl Morpholino thyMine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibiting DNA synthesis, induction of apoptosis, etc.

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