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O-TOLUIDINE HYDROCHLORIDE

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O-TOLUIDINE HYDROCHLORIDE Basic information

Product Name:
O-TOLUIDINE HYDROCHLORIDE
Synonyms:
  • o-Tolidine hydroch
  • o-ToluidineHCL
  • ORTHO-TOLUIDINEHCL
  • ORTHO-TOLUIDINEHYDROCHLORIDE
  • Prilocaine Related Compound A (100 mg) (o-toluidine hydrochloride)
  • Prilocaine Related CoMpound A
  • Prilocaine EP Impurity B
  • Prilocaine impurity B
CAS:
636-21-5
MF:
C7H10ClN
MW:
143.61
EINECS:
211-252-8
Product Categories:
  • amine
Mol File:
636-21-5.mol
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O-TOLUIDINE HYDROCHLORIDE Chemical Properties

Melting point:
215-217 °C(lit.)
Boiling point:
242 °C
Density 
1.0968 (rough estimate)
refractive index 
1.5760 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
color 
White to Grey
BRN 
3558629
Stability:
Stable. Incompatible with oxidizing agents, alkalies. Light and moisture sensitive.
InChIKey
OGVXWEOZQMAAIM-UHFFFAOYSA-N
CAS DataBase Reference
636-21-5(CAS DataBase Reference)
EPA Substance Registry System
o-Toluidine hydrochloride (636-21-5)
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Safety Information

Hazard Codes 
T
Risk Statements 
45-20/21/22
Safety Statements 
53-36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
XU7350000
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
2921430000
Hazardous Substances Data
636-21-5(Hazardous Substances Data)

MSDS

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O-TOLUIDINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of more than 90 dyes and pigments (NCI 1979, IARC 1982, 2000). They are used in acid-fast dyestuffs, azo pigments and dyes, triarylmethane dyes, sulfur dyes, and indigo compounds and as a photographic dye. o-Toluidine is also used as an intermediate for synthetic rubber and rubber vulcanizing chemicals, pharmaceuticals, and pesticides and as a curing agent in epoxy resin systems. Other minor uses of o-toluidine and its hydrochloride salt are as an intermediate in organic synthesis and as an ingredient in a clinical laboratory reagent for glucose and hemoglobin analyses.

Uses

o-Toluidine Chloride is a carcinogenic and toxic aromatic amine contained in hair dye, henna and dyed hair samples. Prilocaine USP Related Compound A

General Description

Green crystals or white crystalline solid. Melting point 215-217°F. Highly toxic.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

O-TOLUIDINE HYDROCHLORIDE acts as a weak acid. Incompatible with oxidizing agents and with alkalis .

Fire Hazard

Flash point data for O-TOLUIDINE HYDROCHLORIDE are not available; however, O-TOLUIDINE HYDROCHLORIDE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also o- TOLUIDINE.

Carcinogenicity

o-Toluidine and o-toluidine hydrochloride are reasonably anticipatedto be human carcinogens based on sufficient evidence of carcinogenicity from studies in experimental animals.

O-TOLUIDINE HYDROCHLORIDESupplier

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