CYANOACRYLIC ACID METHYL ESTER Chemical Properties

Melting point:

-40 °C

Boiling point:

bp 48-49°

Density 

nD25 1.443. d20 1.1044

vapor pressure 

49hPa at 20℃

refractive index 

n20D 1.4459

form 

Colorless liquid

LogP

0.24 at 25℃ and pH7

EPA Substance Registry System

Methyl 2-cyanoacrylate (137-05-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25-26

Hazardous Substances Data

137-05-3(Hazardous Substances Data)

Toxicity

guinea pig,LD50,skin,> 10959mg/kg (10959mg/kg),"Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 6, Pg. 965, 1991.

CYANOACRYLIC ACID METHYL ESTER Usage And Synthesis

Description

Methyl cyanoacrylate (MCA) is an organic compound that contains several functional groups, a methyl ester, a nitrile, and an alkene. It is a colorless liquid with low viscosity. Its chief use is as the main component of cyanoacrylate glues.It can be encountered under many trade names. Methyl cyanoacrylate is less commonly encountered than ethyl cyanoacrylate.
It is soluble in acetone, methyl ethyl ketone, nitro methane, and dichloromethane. MCA polymerizes rapidly in presence of moisture.

Chemical Properties

Colorless liquid.

Chemical Properties

Methyl cyanoacrylate is a thick, clear liquid adhesive. The odor threshold is 2.2 ppm.

Uses

Surgical aid (tissue adhesive).

Uses

In high-bond strength, fast-acting glues (e.g., Krazy Glue); surgical use as tissue adhesive

General Description

Clear slightly yellow liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

CYANOACRYLIC ACID METHYL ESTER is an unsaturated aliphatic nitrile and ester. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Hazard

Toxic by inhalation. Eye and upper respi-ratory tract irritant.

Health Hazard

Methyl 2-cyanoacrylate is an irritant of the eyes and nose and can induce occupational asthma.

Fire Hazard

Flash point data for CYANOACRYLIC ACID METHYL ESTER are not available but CYANOACRYLIC ACID METHYL ESTER is probably non-flammable.

Safety Profile

Moderately toxic by ingestion and inhalation routes. Experimental reproductive effects. A human eye irritant. Can bond the eyelids or skin surfaces instantly. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and CN-.

Safety

Heating the polymer causes depolymerization of the cured MCA, producing gaseous products strongly irritant to lungs and eyes.

Potential Exposure

Methyl 2-cyanoacrylate is used in production of coatings and textiles; in the manufacture of quick-setting, high-strength, adhesive cements. Often found around the home; bonds eyes and skin in seconds. Keep out of the reach of children.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifing upper and lower lids. Seek med-facility. When this chemical has been swallowed, get medi-cal attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24- -48 h afterbreathing overexposure， as pulmonaryedema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a cortico-steroid spray.

storage

Color Code- -Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with this chemical you should be trainedon its proper handling and storage. Methyl 2-cyanoacrylateals or peroxides, since violent reactions occur. Store in orig-inal containers under refrigerated conditions at 2- -8℃.Where possible, automatically pump liquid from drums orother storage containers to process containers.

Shipping

UN3334 Aviation regulated liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material. Technical Name Required.

Incompatibilities

Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic, and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur). Reacts violently with water, bases, and peroxides. Contact with alcohols, water, amines, and alkalis can cause rapid polymerization

CYANOACRYLIC ACID METHYL ESTER(137-05-3)Related Product Information

• ETHYL 2-CYANOACRYLATE
• ETHYL ALPHA-CHLOROPHENYLACETATE
• Coumarin 337
• ETHYL 2-CYANO-3-METHYLCROTONATE
• Ethyl (ethoxymethylene)cyanoacetate
• Ethyl 2-cyano-3,3-diphenylacrylate
• ALPHA-CYANOCINNAMIC ACID ETHYL ESTER
• Ethyl 2-cyano-3-(dimethylamino)acrylate
• 3-Cyano-7-hydroxycoumarin
• 3-CYANO-7-METHOXYCOUMARIN
• ETHYL 2-CYANO-3-(2-THIENYL)ACRYLATE
• CYANO-CYCLOPENTYLIDENE-ACETIC ACIDMETHYL ESTER
• ETHYL 2-CYANO-3-(4-NITROPHENYL)PROP-2-ENOATE
• ETHYL 3-(4-CHLOROPHENYL)-2-CYANOACRYLATE
• ETHYL 2-CYANO-3-(4-METHOXYPHENYL)ACRYLATE
• DIETHYL DICYANOFUMARATE, 97
• ETHYL 3-(1,3-BENZODIOXOL-5-YL)-2-CYANOACRYLATE
• Methyl alpha-cyanocinnamate