Mouse IL-4 ELISA Kit Chemical Properties

storage temp. 

-20°C

Safety Information

Storage Class

8B - Non-combustible corrosive hazardous materials

Hazard Classifications

Met. Corr. 1

Mouse IL-4 ELISA Kit Usage And Synthesis

Uses

For research use only. Not for use in diagnostic procedures.
Mouse IL-4 ELISA kit has been used for determining the levels of IL-4 in serum sample.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biological Activity

IL-4 (interleukin 4) is a pleiotropic cytokine. It regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 (T helper) cells, characterized by their cytokine-secretion profile th at includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 (immunoglobulin G1) and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. IL-4 helps in long-term recovery after cerebral ischemia by controlling the activities of microglia/macrophage. In mice, absence of IL-4 is associated with a state anxiety-like behavior.

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