8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Chemical Properties

Boiling point:

511.8±50.0 °C(Predicted)

Density 

1.079±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: >30 mg/ml (from PGF2a isopropy; DMSO: >50 mg/ml (from PGF2a isopropy; Ethanol: >50 mg/ml (from PGF2a isopropy; PBS pH 7.2: <50 μg/ml (from PGF2a isopropy

pka

13.79±0.60(Predicted)

8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Usage And Synthesis

Description

8-iso PGE₂ isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE₂. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.

8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER(330589-21-4)Related Product Information

• Prostaglandin E2
• 8-ISO PROSTAGLANDIN E2