1-BOC-2-BENZYL-PIPERIDIN-4-ONE
1-BOC-2-BENZYL-PIPERIDIN-4-ONE Basic information
- Product Name:
- 1-BOC-2-BENZYL-PIPERIDIN-4-ONE
- Synonyms:
-
- 1-BOC-2-BENZYL-PIPERIDIN-4-ONE
- 1-N-BOC-2-BENZYL-PIPERIDIN-4-ONE
- 1-Piperidinecarboxylicacid,4-oxo-2-(phenylMethyl)-,1,1-diMethylethylester
- 1-Boc-2-Benzyl-4-piperidine
- 1-Boc-2-Benzyl-4-piperidinone
- 4-oxo-2-(phenylmethyl)-1-piperidinecarboxylic acid tert-butyl ester
- CAS:
- 193480-28-3
- MF:
- C17H23NO3
- MW:
- 289.37
- EINECS:
- 200-589-5
- Product Categories:
-
- Piperidine
- Piperidines
- Mol File:
- 193480-28-3.mol
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1-BOC-2-BENZYL-PIPERIDIN-4-ONE Chemical Properties
- Melting point:
- 79-80o C
- Boiling point:
- 409.0±38.0 °C(Predicted)
- Density
- 1.115±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -1.58±0.40(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 193480-28-3(CAS DataBase Reference)
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1-BOC-2-BENZYL-PIPERIDIN-4-ONE Usage And Synthesis
Synthesis
193469-44-2
34619-03-9
193480-28-3
2-Benzylpiperidin-4-one (17 g) and di-tert-butyl carbonate (21.8 g) were mixed in dichloromethane (500 ml). The reaction mixture was stirred at room temperature for 48 hours. After completion of the reaction, the solvent was removed by rotary evaporation. The organic layer was separated by dissolving the residue in water and toluene. The aqueous layer was extracted again with toluene. All organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated to give 38 g (100% yield) of (±)-1-tert-butoxycarbonyl-2-benzyl-4-piperidone (Intermediate 6).
References
[1] Patent: US6346540, 2002, B1. Location in patent: Page column 17
1-BOC-2-BENZYL-PIPERIDIN-4-ONESupplier
Meryer (Shanghai) Chemical Technology Co., Ltd.
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- 4006356688 18621169109
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Capot Chemical Co., Ltd
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- +86 (0) 571 85 58 67 18
Tetranov Biopharm
- Tel
- 13526569071
- sales@leadmedpharm.com
Shanghai Hanhong Scientific Co.,Ltd.
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- 021-54306202 13764082696
- info@hanhongsci.com
Innochem(Beijing) Technology Co.,Ltd.
- Tel
- 010-56541685 13070143590
- sales@innochem.cn
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1-BOC-2-BENZYL-PIPERIDIN-4-ONE(193480-28-3)Related Product Information
- 1-BOC-3-BENZYL-PIPERIDIN-4-ONE
- 2-BENZYL-PIPERIDIN-4-ONE
- CIS-2-HYDROXY-1-CYCLOPENTANECARBOXYLIC ACID,99%
- TERT-BUTYL (2S)-2-BENZYL-4-OXOPIPERIDINE-1-CARBOXYLATE
- N-Carbethoxy-4-piperidone
- 1-BOC-2-METHYL-PIPERIDIN-4-ONE
- TERT-BUTYL (2R)-2-BENZYL-4-OXOPIPERIDINE-1-CARBOXYLATE
- 1-BOC-2-ETHYL-PIPERIDIN-4-ONE
- 1-BOC-2-BENZYL-PIPERIDIN-4-ONE