Idarucizumab Usage And Synthesis

Uses

Idarucizumab is a humanized monoclonal antibody fragment. Idarucizumab is first reversal agent for a direct oral anticoagulant (DOAC). Idarucizumab can specifically neutralize the effects of the oral direct thrombin inhibitor in order to restore hemostasis[1].

References

[1] Finks SW, et al. Idarucizumab (Praxbind): The First Reversal Agent for a Direct Oral Anticoagulant. Am J Med. 2017 May;130(5):e195-e197. DOI:10.1016/j.amjmed.2016.11.029

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