5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE
5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE Basic information
- Product Name:
- 5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE
- Synonyms:
-
- 5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE
- RS 100329 HYDROCHLORIDE
- 5-Methyl-3-[3-[3-[4-[2-(2,2,2,-trifluroethoxy)phenyl]-1-piperazinyl]propyl]-2,4-(1H,3H)-pyrimidinedionehydrochloride
- RS100329HCl
- 2,4(1H,3H)-PyriMidinedione, 5-Methyl-3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-
- 5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE
- CAS:
- 232953-52-5
- MF:
- C20H25F3N4O3
- MW:
- 426.43
- Mol File:
- 232953-52-5.mol
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5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE Chemical Properties
- storage temp.
- Store at RT
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5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE Usage And Synthesis
Uses
RS 100329 Hydrochloride is a useful intermediate.
Biological Activity
Subtype-selective α 1A -adrenoceptor antagonist (pK i = 9.6 for human cloned α 1A receptors). Displays 126- and 50-fold selectivity over human α 1B and α 1D receptors respectively. Active in vivo .
5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDESupplier
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5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE(232953-52-5)Related Product Information
- 1-(2-ETHOXYPHENYL)PIPERAZINE
- N-(3-AMINOPROPYL) METHACRYLAMIDE
- 1-(2-Methoxyphenyl)piperazine hydrobromide
- 2-(2-FLUORO-ETHOXY)-PHENYLAMINE
- 1-(2-ETHOXYPHENYL)PIPERAZINE HYDROCHLORIDE
- Dimethylamino propyl methacrylamide
- 5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE
- 2-(2,2,2-TRIFLUOROETHOXY)ANILINE