N-(3-AMINOPROPYL) METHACRYLAMIDE Chemical Properties

Melting point:

123-128°C

storage temp. 

2-8°C

form 

powder

Appearance

White to off-white Solid

InChI

InChI=1S/C7H14N2O.ClH/c1-6(2)7(10)9-5-3-4-8;/h1,3-5,8H2,2H3,(H,9,10);1H

InChIKey

XHIRWEVPYCTARV-UHFFFAOYSA-N

SMILES

C(=O)(C(=C)C)NCCCN.Cl

EPA Substance Registry System

2-Propenamide, N-(3-aminopropyl)-2-methyl-, monohydrochloride (72607-53-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/38

Safety Statements 

26

WGK Germany 

3

HS Code 

29241990

N-(3-AMINOPROPYL) METHACRYLAMIDE Usage And Synthesis

Uses

APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.

General Description

N-(3-Aminopropyl)methacrylamide hydrochloride (APMA) is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.

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