5-Bromo-4-fluoro-1-methyl-1H-indazole Chemical Properties

Boiling point:

293.4±20.0 °C(Predicted)

Density 

1.70±0.1 g/cm3(Predicted)

pka

-0.38±0.30(Predicted)

InChI

InChI=1S/C8H6BrFN2/c1-12-7-3-2-6(9)8(10)5(7)4-11-12/h2-4H,1H3

InChIKey

ANLXRMBQONDZBQ-UHFFFAOYSA-N

SMILES

N1(C)C2=C(C(F)=C(Br)C=C2)C=N1

5-Bromo-4-fluoro-1-methyl-1H-indazole Usage And Synthesis

Description

5-Bromo-4-fluoro-1-methyl-1h-indazole is an intermediate component in the synthesis of Orforglipron. Orforglipron is a small-molecule, non-peptide GLP-1 receptor agonist indicated for weight reduction and type 2 diabetes. It is currently in Phase 3 clinical trials.

Uses

5-Bromo-4-fluoro-1-methyl-1H-indazole is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.