Basic information Safety Supplier Related

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin

Basic information Safety Supplier Related

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Basic information

Product Name:
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
Synonyms:
  • CPM
  • AURORA KA-6719
  • 7-DIETHYLAMINO-3-(4-MALEIMIDOPHENYL)-4-METHYLCOUMARIN
  • 7-DIETHYLAMINO-3-(4'-MALEIMIDYLPHENYL)-4-METHYLCOUMARIN
  • 7-DIETHYLAMINO-3-(4-MALEIMIODOPHENYL)-4-METHYLCOUMARIN
  • 1H-PYRROLE-2,5-DIONE, 1-(4-(7-(DIETHYLAMINO)-4-METHYL-2-OXO-2H-1-BENZOPYRAN-3-YL)PHENYL)-
  • 1-[4-(7-Diethylamino-4-methyl-2-oxo-2H-chromen-3-yl)-phenyl]-pyrrole-2,5-dione
  • 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcumarin
CAS:
76877-33-3
MF:
C24H22N2O4
MW:
402.44
Product Categories:
  • Coumarines
Mol File:
76877-33-3.mol
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7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Chemical Properties

Melting point:
220-223°C
Boiling point:
618.7±55.0 °C(Predicted)
Density 
1.302±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble
pka
3.28±0.20(Predicted)
form 
solid
color 
yellow
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Safety Information

WGK Germany 
3
10

MSDS

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7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Usage And Synthesis

Description

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.

Uses

(7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin)CPM is probably the most widely used blue fluorescent thiol-reactive dye. This maleimide derivative of coumarin is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. CPM is a good energ

Uses

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM) is a thiol-reactive fluorescent probe. CPM selectively forms Michael adducts in the presence of hyperreactive sulfhydryls. CPM has been used to monitor the release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining. Dyes and metabolites.

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