7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Basic information
- Product Name:
- 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
- Synonyms:
-
- CPM
- AURORA KA-6719
- 7-DIETHYLAMINO-3-(4-MALEIMIDOPHENYL)-4-METHYLCOUMARIN
- 7-DIETHYLAMINO-3-(4'-MALEIMIDYLPHENYL)-4-METHYLCOUMARIN
- 7-DIETHYLAMINO-3-(4-MALEIMIODOPHENYL)-4-METHYLCOUMARIN
- 1H-PYRROLE-2,5-DIONE, 1-(4-(7-(DIETHYLAMINO)-4-METHYL-2-OXO-2H-1-BENZOPYRAN-3-YL)PHENYL)-
- 1-[4-(7-Diethylamino-4-methyl-2-oxo-2H-chromen-3-yl)-phenyl]-pyrrole-2,5-dione
- 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcumarin
- CAS:
- 76877-33-3
- MF:
- C24H22N2O4
- MW:
- 402.44
- Product Categories:
-
- Coumarines
- Mol File:
- 76877-33-3.mol
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Chemical Properties
- Melting point:
- 220-223°C
- Boiling point:
- 618.7±55.0 °C(Predicted)
- Density
- 1.302±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- pka
- 3.28±0.20(Predicted)
- form
- solid
- color
- yellow
Safety Information
- WGK Germany
- 3
- F
- 10
MSDS
- Language:English Provider:SigmaAldrich
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Usage And Synthesis
Description
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.
Uses
(7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin)CPM is probably the most widely used blue fluorescent thiol-reactive dye. This maleimide derivative of coumarin is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. CPM is a good energ
Uses
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM) is a thiol-reactive fluorescent probe. CPM selectively forms Michael adducts in the presence of hyperreactive sulfhydryls. CPM has been used to monitor the release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining. Dyes and metabolites.
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7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin(76877-33-3)Related Product Information
- 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL
- 4-AMINO-4'-(N,N-DIMETHYLAMINO)STILBENE
- 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
- 1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE
- N-(4-VINYLPHENYL)MALEIMIDE
- 4-Aminophenylacetic acid
- N-(4-ETHYLPHENYL)MALEIMIDE
- 4-METHYL-3-PHENYLCOUMARIN
- 4-(DIMETHYLAMINO)PHENYLACETIC ACID
- 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE
- ALPHA-PHENYL-CIS-CINNAMIC ACID
- 7-Diethylamino-4-methylcoumarin
- Actarit
- 7-Dimethylamino-4-methylcoumarin
- TRANS-4-ACETYL-AMINOSTILBENE
- 3-PHENYLCOUMARIN
- 2-(4-(DIMETHYLAMINO)PHENYL)ACETALDEHYDE
- 2-STYRYLBENZENOL