Basic information Safety Supplier Related

RAMOSETRON

Basic information Safety Supplier Related

RAMOSETRON Basic information

Product Name:
RAMOSETRON
Synonyms:
  • RAMOSETRON
  • (-)-(R)-1-Methylindol-3-yl 4,5,6,7-tetrahydro-5-benzimidazolylketone
  • Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (R)-
  • Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]- (9CI)
  • Nasea
  • Nor-YM 060
  • (R)-5-[(1-METHYLINDOLE-3-YL)CARBONYL]-4,5,6,7-TETRAHYDRO-1H-BEZIMIDAZOLE, 98+%
  • (1-Methyl-1H-indol-3-yl)[[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol]-5α-yl] ketone
CAS:
132036-88-5
MF:
C17H17N3O
MW:
279.34
Mol File:
132036-88-5.mol
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RAMOSETRON Chemical Properties

alpha 
D20 -16.5° (c 1.13 in methanol)
Boiling point:
579.7±50.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
14.53±0.40(Predicted)
InChI
InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1
InChIKey
NTHPAPBPFQJABD-LLVKDONJSA-N
SMILES
C(C1C2=C(N(C)C=1)C=CC=C2)([C@H]1CC2NC=NC=2CC1)=O
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RAMOSETRON Usage And Synthesis

Uses

Ramosetron is a serotonin 5HT3 receptor antagonist.

Definition

ChEBI: Ramosetron is a member of indoles.

in vivo

Ramosetron (0.01-0.1 mg/kg, p.o., twice daily for 5 days) Ameliorates 5-fluorouracil (5-FU) (HY-90006)-induced intestinal mucositis in C57BL/6 mice[2].

IC 50

5-HT3 Receptor

RAMOSETRONSupplier

Suizhou HongQi Chemical Corporation Limited Gold
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0722-3257376 13026100080
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185
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HangZhou YuHao Chemical Technology Co., Ltd.
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0571-82693216
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info@yuhaochemical.com
Hotechem Shanghai Co., Ltd.,
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021-34621078 13120882795
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465106944@qq.com
Pharmacodia (Beijing) Co.,Ltd
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+86-400-851-9921
Email
sales@pharmacodia.com
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