CINITAPRIDE HYDROGEN TARTRATE Chemical Properties

Melting point:

>197°C (dec.)

Boiling point:

579.8±50.0 °C(Predicted)

Density 

1.24

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

pka

12.62±0.20(Predicted)

form 

Solid

color 

Yellow

CINITAPRIDE HYDROGEN TARTRATE Usage And Synthesis

Description

Cinitapride is a substituted benzamide dopamine receptor antagonist effective in the treatment of gastroesophageal reflux and a variety of gastrointestinal motility disorders. It generates strong procholinergic activity in the gastrointestinal tract by elevating the serotonergic transmission in the mysenteric plexus.

Chemical Properties

White Solid

Originator

Almirall (Spain)

Uses

A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).

Uses

serotonin-norepinephrine reuptake inhibitor, antidepressant

Definition

ChEBI: Cinitapride is an aromatic ether and a C-nitro compound.

brand name

Cidine

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