1,3-Dichloroisoquinoline Chemical Properties

Melting point:

121-122 °C (lit.)

Boiling point:

307°C(lit.)

Density 

1.407±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

form 

powder to crystal

pka

-1.49±0.50(Predicted)

color 

Light yellow to Brown to Dark green

CAS DataBase Reference

7742-73-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich

1,3-Dichloroisoquinoline Usage And Synthesis

Chemical Properties

White to brown crystalline powder

Uses

1,3-Dichloroisoquinoline may be used in the facile synthesis of 1,3,4-trisubstituted isoquinoline derivatives.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 5481, 1958 DOI: 10.1021/ja01553a042

General Description

1,3-Dichloroisoquinoline undergoes Pd(PPh₃)₄ catalyzed regioselective coupling with arylboronic acids to afford to 1-aryl-3-chloroisoquinolines. Reaction of amine with 1,3-dichloroisoquinoline has been studied. Regioselectivity of the Stille coupling reaction of (1-ethoxyvinyl)tri(n-butyl)stannane with 1,3-dichloroisoquinoline has been investigated.

1,3-Dichloroisoquinoline(7742-73-6)Related Product Information

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