Basic information Safety Supplier Related

(-)-BICUCULLINE METHOCHLORIDE

Basic information Safety Supplier Related

(-)-BICUCULLINE METHOCHLORIDE Basic information

Product Name:
(-)-BICUCULLINE METHOCHLORIDE
Synonyms:
  • [R-(R*,S*)]-5-(6,8-DIHYDRO-8-OXOFURO[3,4-E]-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLINIUM CHLORIDE
  • (-)-BICUCULLINE METHOCHLORIDE
  • [R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride
  • l-Bicuculline methochloride
  • 1,3-Dioxolo[4,5-g]isoquinolinium,5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-,chloride (1:1), (5R)-
  • (?)-Bicuculline methochloride
  • ( ) Bicuculline methochloride,()Bicuculline methochloride
  • (-)-Bicuculline methylchloride
CAS:
53552-05-9
MF:
C21H20ClNO6
MW:
417.84
Product Categories:
  • GABA/Glycine receptor
  • GABA
Mol File:
53552-05-9.mol
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(-)-BICUCULLINE METHOCHLORIDE Chemical Properties

storage temp. 
Store at RT
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
Powder
Water Solubility 
Soluble to 100 mM in water
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(-)-BICUCULLINE METHOCHLORIDE Usage And Synthesis

Uses

(-)-Bicuculline Methochloride is a GABA receptor inhibitor. Convulsant.

Biological Activity

Methochloride salt of (+)-bicuculline ([R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one ). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

target

GABA Receptor

(-)-BICUCULLINE METHOCHLORIDESupplier

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