L-PHENYLALANINE (3-13C) Chemical Properties

Melting point:

270-275 °C (dec.)(lit.)

form 

Solid

color 

White to off-white

optical activity

[α]25/D -33.0°, c = 1 in H2O

Safety Information

WGK Germany 

3

MSDS

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L-PHENYLALANINE (3-13C) Usage And Synthesis

Uses

L-Phenylalanine-3-13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

IC 50

NMDA Receptor

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110

L-PHENYLALANINE (3-13C)(136056-02-5)Related Product Information

• L-ALANINE (3-13C)