6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE Chemical Properties

Melting point:

63-65 °C(lit.)

Boiling point:

396.8±35.0 °C(Predicted)

Density 

1.29±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMF: soluble(lit.)

form 

Solid

color 

White to Off-White

BRN 

1241835

InChIKey

AXJVPXNVESYGDT-UHFFFAOYSA-N

CAS DataBase Reference

5617-70-9(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2932209090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE Usage And Synthesis

Uses

6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 7, p. 411, 1990
The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)Related Product Information

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• 1,1-Cyclopropanedicarboxylic acid
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• 1,1-CYCLOPROPANEDICARBOXYLIC ACID MONOETHYL ESTER
• Ethyl cyclopropanecarboxylate
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