1,1-Cyclopropanedicarboxylic acid Chemical Properties

Melting point:

134-136 °C(lit.)

Boiling point:

200.75°C (rough estimate)

Density 

1.3985 (rough estimate)

refractive index 

1.5800 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

methanol: soluble1g/10 mL, clear, colorless

pka

1.82(at 25℃)

form 

powder to crystal

color 

White to Almost white

Water Solubility 

Soluble

BRN 

1864823

InChI

InChI=1S/C5H6O4/c6-3(7)5(1-2-5)4(8)9/h1-2H2,(H,6,7)(H,8,9)

InChIKey

FDKLLWKMYAMLIF-UHFFFAOYSA-N

SMILES

C1(C(O)=O)(C(O)=O)CC1

CAS DataBase Reference

598-10-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,C

Risk Statements 

36/37/38-34

Safety Statements 

26-36-45-36/37/39

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

8

PackingGroup 

III

HS Code 

29172090

MSDS

• Language:English Provider:1,1-Cyclopropanedicarboxylic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,1-Cyclopropanedicarboxylic acid Usage And Synthesis

Chemical Properties

white to almost white crystalline powder

Uses

1,1-Cyclopropanedicarboxylic acid, is used as an inhibitor of 1-aminocyclopropane-1-carboxylic acid oxidase, was quantitated in Lycopersicum esculentum by HPLC-electrospray tandem mass spectrometry. Crystal and molecular structure of cyclopropane-1,1-dicarboxylic acid has been reported. Cyclopropane-1,1-dicarboxylic acid was used in the preparation of new heterocyclic derivatives of cyclopropane dicarboxylic acid containing thiadiazole and 1,2,4-triazole moieties. It was also used to prepare spiro-cyclopropyl metallocycles. It can also be used as a building block for the synthesis of a series of cyclopropanecarboxamides, having antifungal activity.

Uses

1,1-Cyclopropanedicarboxylic acid is used to prepare spiro-cyclopropyl metallocycles.1

General Description

Cyclopropane-1,1-dicarboxylic acid is a dicarboxylic acid. Cyclopropane-1,1-dicarboxylic acid, an inhibitor of 1-aminocyclopropane-1-carboxylic acid oxidase, was quantitated in Lycopersicum esculentum by HPLC-electrospray tandem mass spectrometry. Crystal and molecular structure of cyclopropane-1,1-dicarboxylic acid has been reported.

Purification Methods

Recrystallise the di-acid from CHCl3, EtOAc or *C6H6/Et2O/pet ether. It forms a monohydrate. [Nicolet & Satler J Am Chem Soc 49 2070 1927, Beilstein 9 II 512, 9 III 3795.]

1,1-Cyclopropanedicarboxylic acid(598-10-7)Related Product Information

• Cyclopropanecarboxylic acid
• OXALIC ACID
• Cyclopropanecarbonitrile
• Cyclohexanecarboxylic acid
• Cyclopropane
• Hyaluronic acid
• N,N-Diisopropylethylamine
• N-Methyl-2-pyrrolidone
• 1,1-Bis(hydroxymethyl)cyclopropane
• Citric acid
• 2,5-PYRIDINEDICARBOXYLIC ACID
• Ethyl 2-(Chlorosulfonyl)acetate
• Folic acid
• Cyclopropyl methyl ketone
• Cyclopropylboronic acid
• 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
• Cyclopropylacetic acid
• cyclobutane-1,3-diol