Cyclopropanecarbonitrile Chemical Properties

Boiling point:

135 °C (lit.)

Density 

0.911 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.421(lit.)

Flash point:

91 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol (Slightly)

form 

Liquid

Specific Gravity

0.905

color 

Clear colorless to faintly yellow

Water Solubility 

Miscible with water.

BRN 

635790

Exposure limits

NIOSH: IDLH 25 mg/m3

CAS DataBase Reference

5500-21-0(CAS DataBase Reference)

NIST Chemistry Reference

Cyclopropanecarbonitrile(5500-21-0)

EPA Substance Registry System

Cyclopropanecarbonitrile (5500-21-0)

Safety Information

Hazard Codes 

T,F

Risk Statements 

10-23/24/25-36/37/38

Safety Statements 

23-26-36/37-45-36/37/39-16-7/9

RIDADR 

UN 3275 6.1/PG 2

WGK Germany 

2

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29269095

MSDS

• Language:English Provider:Cyclopropyl cyanide
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Cyclopropanecarbonitrile Usage And Synthesis

Chemical Properties

clear colorless to faintly yellow liquid

Uses

Cyclopropanecarbonitrile is a cyano substituted cycloalkane. Cyclopropanecarbonitrile is an Impurity of pazufloxacin mesylate (P211000).

Uses

Cyclopropanecarbonitrile is used to prepare cis and trans crotonitrile and allyl cyanide. Further, it reacts with phenylmagnesium bromide to give cyclopropyl-phenyl ketone-imine.

Application

Cyclopropane formonitrile is a nitrile compound with cyclopropane structural units, which has important applications in organic synthesis, especially in the fields of medicine and pesticides. It can be used to prepare cis- and trans-crotonium nitrile, as well as allyl cyanide. It can also react with Grignard reagents such as magnesium phenyl bromide.

Synthesis

There are many methods for synthesizing cyclopropaneformitrile. A common industrial synthetic route uses 4-chlorobutyronitrile as a starting material and carries out an intramolecular cyclization reaction under alkaline conditions (such as sodium hydroxide (NaOH)) to generate a cyclopropane ring.

Cyclopropanecarbonitrile(5500-21-0)Related Product Information

• Propylthiouracil
• 1,1-Bis(hydroxymethyl)cyclopropane
• Phosphonitrilic chloride trimer
• Allyl glycidyl ether
• Copper(I) Cyanide
• N,N-Diisopropylethylamine
• Cyclopropyl methyl ketone
• Cyclopropyl bromide
• Cyclopropylboronic acid
• Cyclopropane
• Allyl bromide
• Cyclopropanecarbonyl Chloride
• 1-PHENYL-1-CYCLOPROPANECARBONITRILE
• 1-(4-CHLOROPHENYL)-1-CYCLOPROPANECARBONITRILE
• 1-Cyano-1-cyclopropanecarboxylic acid
• ETHYL 1-CYANOCYCLOPROPANECARBOXYLATE
• 1-(4-Methylphenyl)-1-cyclopropanecarbonitrile,1-(4-Methylphenyl)cyclopropanecarbonitrile
• POTASSIUM CYANIDE