3'-BROMO-4'-METHYLACETOPHENONE Chemical Properties

Melting point:

42-46 °C(lit.)

Boiling point:

118°C/3mmHg(lit.)

Density 

1.388±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

Off-White to Pale Yellow

Safety Information

WGK Germany 

3

HS Code 

2914390090

MSDS

• Language:English Provider:SigmaAldrich

3'-BROMO-4'-METHYLACETOPHENONE Usage And Synthesis

Uses

3''-Bromo-4''-methylacetophenone is used as a starting material in the synthesis of mansonone E which is used to make mansonone E dervivatives. These derivatives are potent inhibitors of topoisomerase II (Topo II) and topoisomerase I (Topo I) and are also potent antitumor agents. 3''-Bromo-4''-methylacetophenone is also used as a reagent in the synthesis of BAF312, Siponimod which has been tested in the treatment of patients suffering from relapsing-remitting multiple sclerosis.

3'-BROMO-4'-METHYLACETOPHENONE(40180-80-1)Related Product Information

• 4'-Bromo-2'-methylacetophenone
• 3'-BROMO-4'-METHYLACETOPHENONE
• 2-bromo-2-methylacetophenone
• 2-Bromo-4'-methylacetophenone
• 4'-Methylacetophenone
• 2-bromo-3-methylacetophenone
• 4'-BROMO-3'-METHYLACETOPHENONE
• ETHYL 6-(3-BROMO-4-METHYLPHENYL)-6-OXOHEXANOATE
• BUTTPARK 148\07-08
• 6-(3-BROMO-4-METHYLPHENYL)-6-OXOHEXANOIC ACID
• ETHYL 7-(3-BROMO-4-METHYLPHENYL)-7-OXOHEPTANOATE
• 7-(3-BROMO-4-METHYLPHENYL)-7-OXOHEPTANOIC ACID
• BUTTPARK 148\07-06
• 4-(3-BROMO-4-METHYLPHENYL)-4-OXOBUTYRIC ACID
• ETHYL 4-(3-BROMO-4-METHYLPHENYL)-4-OXOBUTYRATE
• 8-(3-BROMO-4-METHYLPHENYL)-8-OXOOCTANOIC ACID
• 5-(3-BROMO-4-METHYLPHENYL)-5-OXOVALERIC ACID
• ETHYL 5-(3-BROMO-4-METHYLPHENYL)-5-OXOVALERATE