2-IODOPHENYLACETONITRILE Chemical Properties

Boiling point:

113-120 °C0.5 mm Hg(lit.)

Density 

1.75 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.618(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

Sensitive 

Light Sensitive

BRN 

2083106

CAS DataBase Reference

40400-15-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

23-26-36

RIDADR 

3276

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

III

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-IODOPHENYLACETONITRILE Usage And Synthesis

Uses

2-Iodophenylacetonitrile may be used in the preparation of:

• 2?-aminobiphen-2-ylacetonitrile
• ethyl (2-iodophenyl)iminoacetate hydrochloride
• 3,4-disubstituted 2-naphthalenamines

• 2-(2-iodophenyl)-2-methylpropanenitrile
• 1-(2-iodophenyl)cyclopentanecarbonitrile
• 5-bromo-2-(2-iodophenyl)pentanenitrile
• 2-(2-iodophenyl)-2-propylpentanenitrile
• 1-(2-iodophenyl)cyclohexanecarbonitrile
• 1-(2-Iodophenyl)cyclopropanecarbonitrile

General Description

2-Iodophenylacetonitrile is a 2-aryl substituted nitrile. It reacts with lactams to form ring-fused isoquinolinones via palladium-catalyzed carboxamidation in tandem with aldol condensation.

2-IODOPHENYLACETONITRILE(40400-15-5)Related Product Information

• Benzothiazole-2-acetonitrile
• DIPHENYLENEIODONIUM CHLORIDE
• 3-IODOPHENYLACETONITRILE,3-IODOPHENYLACETONITRILE
• 4-IODOPHENYLACETONITRILE
• 2-Iodotoluene
• 2-ETHYLIODOBENZENE
• 2-IODOPHENYLACETONITRILE