N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Chemical Properties

Melting point:

>152°C (dec.)

Boiling point:

936.9±65.0 °C(Predicted)

Density 

1.32±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

9.82±0.70(Predicted)

form 

Solid

color 

Off-White to Pale Yellow

Stability:

Hygroscopic

N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Usage And Synthesis

Uses

N2''-Deacetyl-N2''-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.