Apixaban Amino Acid Impurity Chemical Properties

Melting point:

>145°C (dec.)

Boiling point:

769.1±60.0 °C(Predicted)

Density 

1.39±0.1 g/cm3(Predicted)

storage temp. 

-20°C, Inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

4.59±0.10(Predicted)

color 

Pale Yellow to Light Yellow

Apixaban Amino Acid Impurity Usage And Synthesis

Uses

Apixaban Open chain Acid Is an open ring impurity of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.

Apixaban Amino Acid Impurity(2206825-87-6)Related Product Information

• Apixaban Impurity 34
• Butanoic acid, 2-[(4-hydroxyphenyl)hydrazono]-3-oxo-, ethyl ester
• Apixaban Related Compound 4
• ethyl 6-(4-(5-chloropentanaMido)phenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
• 1-(4-Methoxyphenyl)-6-(4-(2-Methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxaMide
• Apixaban IMpurity 5 (BMS-591329-01)
• 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
• Apixaban Impurity 43
• Apixaban Impurity 37
• Apixaban Impurity 30
• Apixaban Impurity 15
• Apixaban-13C-D3
• ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
• Apixaban Impurity 28
• Apixaban Dehydro Impurity
• Apixaban Impurity 21
• 1-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one
• Apixaban Impurity 40