Basic information Safety Supplier Related

IMIDAPRILAT

Basic information Safety Supplier Related

IMIDAPRILAT Basic information

Product Name:
IMIDAPRILAT
Synonyms:
  • (4S)-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
  • IMIDAPRILAT
  • (4S)-3-{(2S)-2-[N-((1S)-1-Carboxy-3-phenylpropyl)amino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic Acid
  • Imidapril Diacid
  • (4S)-3-[(2S)-N-[(1S)-1-Carboxy-3-phenylpropyl]alanyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid
  • 6366A
  • Imidaprilate
  • 4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)-
CAS:
89371-44-8
MF:
C18H23N3O6
MW:
377.39
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
89371-44-8.mol
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IMIDAPRILAT Chemical Properties

Melting point:
180-1820C
alpha 
D19 -88.4° (c = 1 in 5% NaHCO3)
Boiling point:
592.1±60.0 °C(Predicted)
Density 
1.356±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
form 
Solid
pka
2.17±0.10(Predicted)
color 
White to Off-White
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IMIDAPRILAT Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

Antihypertensive.

Definition

ChEBI: Imidaprilat is a member of the class of imidazolidines that is imidapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of imidapril used to treat hypertension. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a drug metabolite. It is a dipeptide, a member of imidazolidines, a secondary amino compound, a dicarboxylic acid and a N-acylurea. It is functionally related to an imidapril.

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