ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > (+/-)-8-PRENYLNARINGENIN
(+/-)-8-PRENYLNARINGENIN
(+/-)-8-PRENYLNARINGENIN Basic information
- Product Name:
- (+/-)-8-PRENYLNARINGENIN
- Synonyms:
-
- (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-butenyl)-4H-1-benzopyran-4-one
- 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- rac 8-Prenylnaringenin
- 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-
- Naringenin 8-Prenyl Racemate
- (+/-)-8-PRENYLNARINGENIN
- CAS:
- 68682-02-0
- MF:
- C20H20O5
- MW:
- 340.37
- EINECS:
- 245-096-7
- Product Categories:
-
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 68682-02-0.mol
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(+/-)-8-PRENYLNARINGENIN Chemical Properties
- Melting point:
- 183-184 °C
- Boiling point:
- 597.6±50.0 °C(Predicted)
- Density
- 1.314±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Light yellow powder
- pka
- 7.70±0.40(Predicted)
- color
- Off-White to Pale Yellow
- Stability:
- Light Sensitive
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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(+/-)-8-PRENYLNARINGENIN Usage And Synthesis
Description
(±)-8-Prenylnaringenin ((±)-8-PN) is a prenylflavonoid with potent estrogenic activity that can be isolated from hops. It inhibits both isoforms of the human estrogen receptor (ER; IC50s = 57 and 68 nM for ERα and ERβ, respectively). (±)-8-PN is effective in vivo, suppressing loss of bone mineral density in ovariectomized rats and blocking changes in tail skin temperature in a rat model of postmenopausal hot flashes.
Uses
8-Prenylnaringenin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding.
Definition
ChEBI: Rac 8-Prenylnaringenin is a member of flavanones.
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