2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 Chemical Properties

Boiling point:

314.3±37.0 °C(Predicted)

Density 

1.31±0.1 g/cm3(Predicted)

2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 Usage And Synthesis

Biological Activity

Bromo-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃(152065-54-8)Related Product Information

• 2H-Pyran, 2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]tetrahydro-
• Br-PEG6-Ms
• 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro-
• Br-PEG9-Ms
• Br-PEG3-MS
• Br-PEG9-THP
• Br-PEG5-Ms
• Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1-methanesulfonate
• Br-PEG7-THP
• Br-PEG8-Ms
• Br-PEG8-THP
• Methanesulfonic acid 2-bromoethyl ester
• Br-PEG6-THP
• Br-PEG7-Ms
• Br-PEG5-THP
• 2-(2-BROMOETHOXY)TETRAHYDRO-2H-PYRAN
• Ethanol, 2-(2-bromoethoxy)-, 1-methanesulfonate
• Br-PEG10-Ms