AZOXYBENZENE Chemical Properties

Melting point:

32-36 °C

Boiling point:

130 °C / 0.9mmHg

Density 

1.16

refractive index 

1.6330 (estimate)

storage temp. 

0-6°C

color 

Yellow, rhombic crystals

Merck 

14,923

BRN 

743984

Dielectric constant

5.1（40℃）

InChIKey

GAUZCKBSTZFWCT-YPKPFQOOSA-N

CAS DataBase Reference

495-48-7(CAS DataBase Reference)

EPA Substance Registry System

Azoxybenzene (495-48-7)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/22

Safety Statements 

28A-28

WGK Germany 

1

RTECS 

CO4025000

TSCA 

Yes

HS Code 

29153100

Hazardous Substances Data

495-48-7(Hazardous Substances Data)

Toxicity

LD50 orl-rat: 620 mg/kg AMIHBC 10,61,54

MSDS

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AZOXYBENZENE Usage And Synthesis

Chemical Properties

ORANGE-YELLOW TO ORANGE CRYSTALS

Uses

Intermediate in organic synthesis.

Uses

Fenazox is used in the synthetic preparation of amides via reductive amidation of esters, which is used in the synthesis of bio-active molecules and natural products.

Definition

ChEBI: Azoxybenzene is an azoxy compound.

General Description

Bright yellow crystals or yellowish-brown solid.

Air & Water Reactions

Dust may form an explosive mixture in air. Insoluble in water.

Reactivity Profile

AZOXYBENZENE is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.

Fire Hazard

Flash point data for AZOXYBENZENE are not available; however, AZOXYBENZENE is probably combustible.

Safety Profile

Poison by subcutaneous route. Moderately toxic by ingestion, skin contact, and other routes. A skin and eye irritant. Mutation data reported. Combustible. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise azobenzene from EtOH or MeOH, and dry it for 4hours at 25o/10-3mm. Sublime it before use. [Bigelow & Palm Org Synth Coll Vol II 57 1943, Beilstein 16 II 326.]

AZOXYBENZENE(495-48-7)Related Product Information

• Azoxybenzene, 4,4'-dimethoxy-
• Azoxybenzene,3,3’,4,4’-tetrachloro
• 4,4'-BIS(N-HEXYLOXY)AZOXYBENZENE
• 4,4'-Bis(ethoxy)azoxybenzene,Azoxybenzene, 4,4'-diethoxy-
• 4,4'-BIS(PENTYLOXY)AZOXYBENZENE,4,4'-Bis(amyloxy)azoxybenzene
• 4,4'-BIS(HEPTYLOXY)AZOXYBENZENE,Azoxybenzene, 4,4'-bis(heptyloxy)-,p,p'-bis(heptyloxy)azoxybenzene
• Azobenzene
• Azoxybenzene-3,3'-disulfonic acid
• AZOXYBENZENE-4,4'-DICARBOXYLIC ACID DIETHYL ESTER
• 4,4'-Bis(nonyloxy)azoxybenzene
• Azoxybenzene-4,4'-dicarboxylic acid
• azoxybenzene,4,4’-bis(dodecoxy)
• Azoxybenzene-4,4'-dicarbaldehyde
• Azoxybenzene-4,4'-dicarboxylic acid dichloride,4,4'-Bis(chlorocarbonyl)azoxybenzene
• Azoxybenzene-3,3'-dicarboxylic acid
• Azoxybenzene-2,2'-diamine
• 4,4'-Di(octyloxy)azoxybenzene,4,4'-Bis(octyloxy)azoxybenzene
• Azoxybenzene-2,2'-dicarboxylic acid