H-TYR-LEU-OH
H-TYR-LEU-OH Basic information
- Product Name:
- H-TYR-LEU-OH
- Synonyms:
-
- TYR-LEU
- H-TYR-LEU-OH
- L-TYROSYL-L-LEUCINE
- TYR-LEU 99% CRYSTALLINE
- tyr-leucrystalline
- tyrosylleucine
- L-Leucine, N-L-tyrosyl-
- (S)-2-((S)-2-AMino-3-(4-hydroxyphenyl)propanaMido)-4-Methylpentanoic acid
- CAS:
- 17355-10-1
- MF:
- C15H22N2O4
- MW:
- 294.35
- Product Categories:
-
- Dipeptides
- Dipeptides and Tripeptides
- Peptides
- Mol File:
- 17355-10-1.mol
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H-TYR-LEU-OH Chemical Properties
- Melting point:
- 280 °C (sublm)(Solv: water (7732-18-5))
- Boiling point:
- 575.9±50.0 °C(Predicted)
- Density
- 1.218±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 3.12±0.10(Predicted)
- form
- Solid
- color
- White to off-white
MSDS
- Language:English Provider:SigmaAldrich
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H-TYR-LEU-OH Usage And Synthesis
Uses
(S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoic Acid is a pharmaceutical agent with ACE inhibitory properties.
Definition
ChEBI: A dipeptide formed from L-tyrosine and L-leucine residues.
in vivo
Tyrosylleucine (YL), administered orally, intracerebroventricularly, or intraperitoneally exhibits a potent antidepressant-like activity in the forced swim and tail suspension tests in na ve mice[1].
| Animal Model: | Male ddY mice (24-27?g)[1] |
| Dosage: | 0.1-30?mg/kg, i.p.; 0.1-1.0 nmol/mouse, i.c.v.; 30-100?mg/kg, p.o. |
| Administration: | Administered orally, intracerebroventricularly, or intraperitoneally |
| Result: | Decreased immobility time after intraperitoneal (1-30?mg/kg) and intracerebroventricular (0.3-1 nmol/mouse) administrations in the FST. Exhibited a potent antidepressant-like activity in the forced swim and tail suspension tests in na?ve mice. |
H-TYR-LEU-OHSupplier
Beijing HwrkChemical Technology Co., Ltd
- Tel
- 18515581800 18501085097
- sales.bj@hwrkchemical.com
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
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H-TYR-LEU-OH(17355-10-1)Related Product Information
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