3-HYDROXYBUTYRONITRILE Chemical Properties

Boiling point:

214 °C (lit.)

Density 

0.976 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.429(lit.)

Flash point:

>230 °F

pka

13.89±0.20(Predicted)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29269095

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

3-HYDROXYBUTYRONITRILE Usage And Synthesis

Chemical Properties

clear slightly yellow to amber liquid

Uses

β-Hydroxybutyronitrile is an intermediate used to prepare 2-Methylazetidine which is a derivative of Azetidine (A813000), a useful building block in the synthesis of polypeptides and other nitrogen containing compounds with potential biological properties.

Definition

ChEBI: 3-hydroxybutanenitrile is a hydroxynitrile that is butyronitirle in which a hydrogen at position 3 has been replaced by a hydroxy group.

General Description

3-Hydroxybutyronitrile is a β-hydroxynitrile derivative. It undergoes thermolysis in the gas-phase through the formation of a six-membered cyclic transition state.

3-HYDROXYBUTYRONITRILE(4368-06-3)Related Product Information

• 3-HYDROXY-3-METHYLBUTYRONITRILE
• (S)-4-Chloro-3-hydroxybutyronitrile
• (R)-4-Cloro-3-Hydroxybutyronitrile,(R)-4-CHLORO-3-HYDROXYBUTYRONITRILE,(R)-(+)-4-CHLORO-3-HYDROXYBUTYRONITRILE
• 2,3,5-Tri-O-benzoyl-beta-D-ribofuranosyl cyanide
• Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
• 2-Methyl-2-hydroxybutyronitrile
• (S)-3,4-DIHYDROXYBUTYRONITRILE
• 1-OXASPIRO[2.5]OCTANE-2-CARBONITRILE
• (+)-CIS-2(R),3(S)-2,3-DIHYDROXY-2,3-DIHYDROBENZONITRILE ACETONIDE
• (+)-CIS-2(R),3(S)-2,3-DIHYDROXY-2,3-DIHYDROBENZONITRILE
• TETRACYANOETHYLENE OXIDE
• 2,2,4-TRIMETHYL-3-HYDROXY-N-VALERONITRILE
• 2,3,4,5-TETRA-O-ACETYL-D-XYLONITRILE
• 1-Oxaspiro[2.4]heptane-2-carbonitrile(6CI,9CI)
• (S)-(+)-3-HYDROXYBUTYRONITRILE
• 3-Methyl-2-hydroxybutyronitrile
• (S)-4-Amino-3-Hydroxybutyronitrile
• (R)-(-)-3-HYDROXYBUTYRONITRILE