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5-(TRIFLUOROMETHOXY)ISATIN

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5-(TRIFLUOROMETHOXY)ISATIN Basic information

Product Name:
5-(TRIFLUOROMETHOXY)ISATIN
Synonyms:
  • 5-(Trifluoromethoxy)isatin 97%
  • 5-(trifluoroMethoxy)-2,3-dihydro-1H-indole-2,3-dione
  • 5-(Trifluoromethoxy)indole-2,3-dione
  • 5-(Trifluoromethoxy)-1H-indole-2,3-dione, 5-(Trifluoromethoxy)indoline-2,3-dione, 2,3-Dihydro-2,3-dioxo-5-(trifluoromethoxy)-1H-indole
  • 5-(TRIFLUOROMETHOXY)ISATIN
  • 5-(TRIFLUOROMETHOXYL)INDOLINE-2,3-DIONE
  • BUTTPARK 34\07-90
  • 5-(Trifluoromethoxy)indoline-2,3-dione
CAS:
169037-23-4
MF:
C9H4F3NO3
MW:
231.13
EINECS:
1592732-453-0
Product Categories:
  • Fused Ring Systems
  • Building Blocks
  • blocks
  • IndolesOxindoles
  • Heterocyclic Building Blocks
  • Indoles
  • Indane/Indanone and Derivatives
Mol File:
169037-23-4.mol
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5-(TRIFLUOROMETHOXY)ISATIN Chemical Properties

Melting point:
170-172 °C(lit.)
Density 
1.562±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
8.49±0.20(Predicted)
form 
powder to crystal
color 
Light yellow to Brown
Water Solubility 
Insoluble in water.
CAS DataBase Reference
169037-23-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
HS Code 
29339900

MSDS

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5-(TRIFLUOROMETHOXY)ISATIN Usage And Synthesis

Uses

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

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