Pyrazolo[1,5-a]pyridine Chemical Properties

Boiling point:

37-39℃/0.2mm

Density 

1.14±0.1 g/cm3(Predicted)

refractive index 

1.6075

storage temp. 

Sealed in dry,Room Temperature

form 

Liquid

pka

2.83±0.30(Predicted)

color 

Colorless to red or brown

Safety Information

HS Code 

2933399990

Pyrazolo[1,5-a]pyridine Usage And Synthesis

Description

Pyrazolo[1,5-a]pyridines, a class of fused heteroaromatic bicyclic compounds, have been investigated for their pharmacological and biological activities. They are used as dopamine D2/D3/D4 antagonists, anti-herpetic agents, p38 kinase inhibitors, PI3 kinase inhibitors, antitubercular agents, EP1 receptor antagonists, 5HT3-antagonists, melatonin receptor (MT1/MT2) ligands, Mcl-1Bcl-xL dual inhibitors, and corticotropin-releasing factor 1 antagonists. Pyrazolo[1,5-a]pyridine has been used as a fluorophore in the research of Zhang et al. and exhibited high quantum yield (0.64, pH 2.4), high selectivity and sensitivity, and extremely short response time[1].

References

[1] Brian A Johns. “Pyrazolo[1,5-a]pyridines: synthetic approaches to a novel class of antiherpetics.” Tetrahedron 59 45 (2003): Pages 9001-9011.

Pyrazolo[1,5-a]pyridine(274-56-6)Related Product Information

• 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
• Zolpidem tartrate
• Pyridine
• Pyraclostrobin
• PYRAZOLO[1,5-A]PYRIDIN-3-YLAMINE
• Pyrazolo[1,5-a]pyridine-2-carboxylic acid
• ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE
• Pyrazolo[1,5-a]pyridine-3-carboxylic acid
• PYRAZOLO[1,5-A]PYRIDINE-7-CARBOXYLIC ACID
• PYRAZOLO[1,5-A]PYRIMIDINE-5-CARBOXYLICACID
• PYRAZOLO[1,5-A]PYRIDIN-2-OL
• 5-Hydroxypyrazolo[1,5-a]pyrimidine
• PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID ETHYL ESTER
• PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE
• PYRAZOLO[1,5-A]PYRIMIDINE
• C-PYRAZOLO[1,5-A]PYRIDIN-7-YL-METHYLAMINE
• PYRAZOLO[1,5-A]PYRIDIN-6-OL
• pyrazolo[1,5-a]pyridine-5-carboxylic acid