Basic information Safety Supplier Related

Dihydro α-Ergocryptine

Basic information Safety Supplier Related

Dihydro α-Ergocryptine Basic information

Product Name:
Dihydro α-Ergocryptine
Synonyms:
  • dihydroergocryptine
  • 9,10α-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'α-(2-methylpropyl)ergotaman-3',6',18-trione
  • Dihydro Ergotamine Impurity 5
  • 9,10α-Dihydro-12'-hydroxy-2'-isopropyl-5'α-(2-methylpropyl)ergotaman-3',6',18-trion
  • 9,10α-Dihydro-12'-hydroxy-2'-isopropyl-5'α-isobutylergotaman-3',6',18-trione
  • Dihydroergokryptine
  • (5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-(1-Methylethyl)-5'-(2-Methylpropyl)ergotaMan-3',6',18-trione
  • 9,10-Dihydroergocryptine
CAS:
25447-66-9
MF:
C32H43N5O5
MW:
577.71
EINECS:
246-993-6
Product Categories:
  • Aromatics, Heterocycles, Inhibitors, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
25447-66-9.mol
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Dihydro α-Ergocryptine Chemical Properties

Melting point:
235 °C (decomp)
Boiling point:
848.7±65.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka
pKa 6.89±0.07(H2O t=24 I≤0.01) (Uncertain)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Dihydro α-Ergocryptine Usage And Synthesis

Uses

Dihydro α-Ergocryptine is a hydrogenated ergot alkaloids, specifically an equiproportional mixture of dihydroergocornine methanesulfonate, dihydroergocristine methanesulfonate, α and β-dihydroergocrytine methanesulfonate in the ratio of 1.5-2.5:1. Dihydro α-Ergocryptine is an α-adrenergic blocker used for the treatment of impaired mental function in the elderly.

Uses

Dihydro α-Ergocryptine is a hydrogenated ergot alkaloids, specifically an equiproportional mixture of dihydroergocornine methanesulfonate, dihydroergocristine methanesulfonate, α and β-dihydroergocrytine methanesulfonate in the ratio of 1.5-2.5:1. Dihydro α-Ergocryptine is an α-adrenergic blocker used for the treatment of impaired mental function in the elderly.

Definition

ChEBI: alpha-Ergocryptine in which a single bond replaces the double bond between positions 9 and 10.

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