ChemicalBook > Product Catalog > Organic Chemistry > Carboxylic acids and derivatives > AP1189 acetate
AP1189 acetate
AP1189 acetate Basic information
- Product Name:
- AP1189 acetate
- Synonyms:
-
- AP1189 acetate
- AP1189
- AP1189 acetate,AP-1189 acetate
- CAS:
- 959850-74-9
- MF:
- C16H18N6O4
- MW:
- 358.36
- Mol File:
- 959850-74-9.mol
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AP1189 acetate Usage And Synthesis
Description
AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ～3-fold.
AP1189 acetateSupplier
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