3-(2-aminopropyl)phenol Chemical Properties

Boiling point:

273.23°C (rough estimate)

Density 

1.0406 (rough estimate)

refractive index 

1.5380 (estimate)

Melting point:

137 °C

pka

9.86±0.10(Predicted)

Safety Information

Toxicity

LD50 scu-mus: 17 mg/kg ARZNAD 15,219,65

3-(2-aminopropyl)phenol Usage And Synthesis

Uses

3-(2-Aminopropyl)phenol is a biologically active compound with significant blood pressure-raising activity. 3-(2-Aminopropyl)phenol can effectively improve the symptoms of orthostatic hypotension in patients. 3-(2-Aminopropyl)phenol can significantly increase blood pressure at rest and when standing after oral administration. 3-(2-Aminopropyl)phenol can help reduce pathological orthostatic adjustment disorders. 3-(2-Aminopropyl)phenol has a relatively small effect on heart rate, and no significant side effects have been observed[1].

Definition

ChEBI: Alpha-Methyl-m-tyramine is a member of amphetamines.

Safety Profile

Poison by subcutaneous andintravenous routes. When heated to decomposition itemits toxic fumes of NOx.

References

[1] [Therapy of orthostatic dysregulation with gepefrin. Study with continuous telemetric blood pressure monitoring] PMID:4002776

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