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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Serine derivatives >  (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

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(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Basic information

Product Name:
(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
Synonyms:
  • H-DL-SER(3,4-DIHYDROXYPHENYL)-OH
  • H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
  • H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SER-OH
  • DL-DOPS
  • DL-THREO-BETA-(3,4-DIHYDROXYPHENYL)SERINE
  • DL-THREO-DOPS
  • D,L-(3,4-DIHYDROXYPHENYL)-SERINE
  • BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
CAS:
3916-18-5
MF:
C9H11NO5
MW:
213.19
EINECS:
223-480-5
Product Categories:
  • Amines
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
3916-18-5.mol
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(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Chemical Properties

Melting point:
202-205°C (dec.)
Boiling point:
549.8±50.0 °C(Predicted)
Density 
1.608±0.06 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
ethanol: 50 mg/mL Solutions should be freshly prepared.
form 
powder
pka
2.09±0.24(Predicted)
color 
off-white to yellow-tan
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Safety Information

WGK Germany 
2
RTECS 
VT9626000

MSDS

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(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Usage And Synthesis

Chemical Properties

White Solid

Uses

A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian.

Definition

ChEBI: Droxidopa is a serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension It has a role as a prodrug, a vasoconstrictor agent and an antihypertensive agent. It is a L-tyrosine derivative and a member of catechols.

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACIDSupplier

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