4-Amino-2,5,6-trichloropyrimidine Chemical Properties

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

Appearance

White to off-white Solid

4-Amino-2,5,6-trichloropyrimidine Usage And Synthesis

Synthesis

The general procedure for the synthesis of 4-amino-2,5,6-trichloropyrimidine from 4-amino-2,6-dichloropyrimidine was as follows: 1 g (6.1 mmol) of 4-amino-2,6-dichloropyrimidine was dissolved in 5 ml of N,N-dimethylformamide (DMF). To this solution 0.98 g (7.32 mmol) of N-chlorosuccinimide (NCS) was added. The reaction mixture was poured into 100 ml of ice water. The precipitate formed was collected by filtration, washed several times with distilled water and dried under vacuum to give 1.4 g (80% yield) of the target product as a white solid. The structure of the product was confirmed by 1H nuclear magnetic resonance (NMR) spectrum (300 MHz, DMSO-d6): δ= 8.24 (d, 2H).

References

[1] Patent: WO2011/121418, 2011, A1. Location in patent: Page/Page column 24-25

4-Amino-2,5,6-trichloropyrimidine(28969-60-0)Related Product Information

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• ALTRENOGEST
• Chloroform
• N1-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-4-METHYLBENZAMIDE
• 4-(m-aminoanilino)-2,5,6-trichloropyrimidine
• 4-Amino-2,5,6-trichloropyrimidine
• AMINO ACIDS
• N1-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-4-(TRIFLUOROMETHYL)BENZENE-1-SULFONAMIDE
• N1-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-3-(TRIFLUOROMETHYL)BENZAMIDE
• N-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)-N'-[4-(TRIFLUOROMETHOXY)PHENYL]UREA
• N-(4-CHLOROPHENYL)-N'-(3-[(2,5,6-TRICHLOROPYRIMIDIN-4-YL)AMINO]PHENYL)UREA