1-(8-Bromo-2,3,6,7-tetrahydrobenzodifuran-4-yl)-2-aminoethane hydrochloride Chemical Properties

Flash point:

2℃

storage temp. 

-20°C

solubility 

DMF: 1 mg/ml; DMSO: 5 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Methanol: 1 mg/ml

form 

A crystalline solid

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-20/21/22-36

Safety Statements 

16-26-36/37

RIDADR 

UN 1648 3 / PGII

WGK Germany 

2

1-(8-Bromo-2,3,6,7-tetrahydrobenzodifuran-4-yl)-2-aminoethane hydrochloride Usage And Synthesis

Description

A group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” furan or dihydrofuran rings fused on the opposite sides of the central benzene ring, have been identified with allegedly potent hallucinogenic effects. 2C-B-FLY is the dihydrodifuran analog of the Schedule I hallucinogen 4-bromo-2,5-dimethoxyphenethylamine (2C-B). It is expected to show similar activity to 2C-B, which acts as a partial agonist at the 5-HT_2A serotonin receptor and demonstrates high binding affinity for the 5-HT_2B and 5-HT_2C serotonin receptors. This product is intended for forensic and research purposes.

Uses

A metabolite of Bromo Dragonfly (B684210).

References

[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] SIMONA PICHINI . Liquid chromatography–atmospheric pressure ionization electrospray mass spectrometry determination of “hallucinogenic designer drugs” in urine of consumers[J]. Journal of pharmaceutical and biomedical analysis, 2008, 47 2: Pages 335-342. DOI: 10.1016/j.jpba.2007.12.039
[3] AARON P. MONTE. Dihydrobenzofuran Analogues of Hallucinogens. 3. 1 Models of 4-Substituted (2,5-Dimethoxyphenyl)alkylamine Derivatives with Rigidified Methoxy Groups 2[J]. Journal of Medicinal Chemistry, 1996, 39 15: 2953-2961. DOI: 10.1021/jm960199j
[4] JAMES J. CHAMBERS. Enantiospecific Synthesis and Pharmacological Evaluation of a Series of Super-Potent, Conformationally Restricted 5-HT2A/2C Receptor Agonists[J]. Journal of Medicinal Chemistry, 2001, 44 6: 1003-1010. DOI: 10.1021/jm000491y

1-(8-Bromo-2,3,6,7-tetrahydrobenzodifuran-4-yl)-2-aminoethane hydrochloride(178557-21-6)Related Product Information

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