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trans-2-(3-Fluorophenyl)vinylboronic acid

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trans-2-(3-Fluorophenyl)vinylboronic acid Basic information

Product Name:
trans-2-(3-Fluorophenyl)vinylboronic acid
Synonyms:
  • trans-2-(3-Fluorophenyl)vinylboronic acid
  • (3-Fluorostyryl)boronic acid
  • (E)-2-(3-Fluorophenyl)ethenylboronic acid
  • Boronic acid, B-[(1E)-2-(3-fluorophenyl)ethenyl]-
  • (E)-(3-Fluorostyryl)boronic acid
CAS:
849062-22-2
MF:
C8H8BFO2
MW:
165.96
Product Categories:
  • blocks
  • BoronicAcids
  • Alkenyl
  • Boronic Acids
  • Boronic Acids and Derivatives
  • 6
Mol File:
849062-22-2.mol
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trans-2-(3-Fluorophenyl)vinylboronic acid Chemical Properties

Melting point:
184-186 °C (lit.)
Boiling point:
313.9±44.0 °C(Predicted)
Density 
1.228±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
9.57±0.43(Predicted)
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Safety Information

WGK Germany 
3
HS Code 
2931900090
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trans-2-(3-Fluorophenyl)vinylboronic acid Usage And Synthesis

Uses

Reactant for:

  • Enantioselective diastereoselective synthesis of tetracyclins via metal-catalyzed ring opening of meso-oxabicyclic alkenes followed by hydrogenation and Friedel-Crafts alkylation
  • Palladium-catalyzed Suzuki-Miyaura coupling reactions
  • Preparation of anticonvulsant agents
  • Preparation of piperazinyl pyrimidylhydroxamic acid deriatives as histone deacetylase inhibitors and antitumor agents
  • Preparation of ethyl-substituted conjugated dienoates and dienones by stereoselective Suzuki cross-coupling

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