HUMAN EOTAXIN Chemical Properties

storage temp. 

−20°C

form 

lyophilized powder

biological source

mouse

Safety Information

Hazard Codes 

T

Risk Statements 

23/24/25-36/37/38

Safety Statements 

26-36/37/39-45

WGK Germany 

3

MSDS

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HUMAN EOTAXIN Usage And Synthesis

Uses

The kit is used for the in vitro quantitative detection of Eotaxin1 concentration in mouse serum, plasma, or other biological fluids.

Biological Activity

Eotaxin is a chemoattractant for eosinophils, and is involved inflammatory diseases, such as asthma. It is induced by glucocorticoids and cytokines. Along with interleukin-5 (IL-5) it results in airway hyperresponsiveness (AHR), and hence, lung inflammatory disorders. In humans, it leads to respiratory syncytial virus (RSV) vaccine-enhanced disease, and the eosinophils are also responsible for the elimination of virus. It might also be involved in the pathophysiology of inflammatory bowel diseases which involve eosinophils. It can lead to the production of reactive oxygen species, thus, resulting in damaged tissue. It is overexpressed in multiple diseases such as allergic rhinitis, nasal polyposis, endometriosis and Hodgkin′s disease.

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