N-Cyclohexyl-2-piperazin-1-yl-acetamide
N-Cyclohexyl-2-piperazin-1-yl-acetamide Basic information
- Product Name:
- N-Cyclohexyl-2-piperazin-1-yl-acetamide
- Synonyms:
-
- N-Cyclohexyl(piperazin-1-yl)acetamide
- N-Cyclohexyl-1-piperazineacetamide
- 1-piperazineacetamide, N-cyclohexyl-
- N-cyclohexyl-2-piperazin-1-ylacetamide dihydrochloride
- {[(Piperazin-1-yl)acetyl]amino}cyclohexane, 1-[2-(Cyclohexylamino)-2-oxoethyl]piperazine
- N-Cyclohexyl-2-piperazin-1-yl-acetamide
- Esaprazole
- N-Cyclohexyl-2-piperazin-1-yl-ace
- CAS:
- 64204-55-3
- MF:
- C12H23N3O
- MW:
- 225.33
- Product Categories:
-
- piperazines
- Mol File:
- 64204-55-3.mol
More
Less
N-Cyclohexyl-2-piperazin-1-yl-acetamide Chemical Properties
- Melting point:
- 111-112°
- Boiling point:
- bp0.5 190°
- Density
- 1.07±0.1 g/cm3(Predicted)
- pka
- 15.27±0.20(Predicted)
More
Less
Safety Information
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933599590
- Toxicity
- LD50 in mice (mg/kg): 1974 orally; 271 i.v.; in rats (mg/kg): 3900 orally (Corvi-Mora)
More
Less
N-Cyclohexyl-2-piperazin-1-yl-acetamide Usage And Synthesis
Uses
Esaprazole (Hexaprazole) is an antiulcer agent that has the effect of promoting the healing of peptic ulcer. Esaprazole can inhibit the secretion of gastric acid and pepsin[1].
in vivo
Esaprazole (50-450 mg/kg; intraduodenal administration; single dose) can inhibit the secretion of gastric acid and pepsin in a dose-dependent manner in Wistar rats. Moreover, Esaprazole (25, 50, and 100 mg/kg; intraperitoneal injection; single dose) can also inhibit the hypersecretion of acid induced by Bethanechol (HY-B0406) (500 μg/kg/h) and the acid secretory response induced by vagal stimulation[1].
References
[1] Blandizzi C, et al. Gastric antisecretory effects of esaprazole in rats. Digestion. 1992;51(4):226-232. DOI:10.1159/000200902
N-Cyclohexyl-2-piperazin-1-yl-acetamideSupplier
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
Wuhan Chemwish Technology Co., Ltd
- Tel
- 86-027-67849912
- sales@chemwish.com
Shanghai Synchem Pharma Co., ltd
- Tel
- 21-619849051-1 18521059765
- synchempharma@aliyun.com
Jiangsu aikang biomedical research and development co., LTD
- Tel
- 025-58859352 13155353615
- qzhang@aikonchem.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
More
Less
N-Cyclohexyl-2-piperazin-1-yl-acetamide(64204-55-3)Related Product Information
- KP 103
- N-(4-methylcyclohexyl)-2-(piperazin-1-yl)acetamide
- N-cyclohexyl-2-(piperazin-1-yl)propanamide
- AURORA 12628
- N-CYCLOHEXYL-2-[4-(4,6-DIANILINO-1,3,5-TRIAZIN-2-YL)-1-PIPERAZINYL]ACETAMIDE
- 4-CYCLOHEXYLCARBAMOYLMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- N-(1-PHENYLCYCLOHEXYL)-2-PIPERAZIN-1-YLACETAMIDE
- N-Cyclohexyl-2-piperazin-1-yl-acetamide
- 2-(4-(BENZO[D]THIAZOL-2-YL)PIPERAZIN-1-YL)-N-CYCLOHEXYLACETAMIDE